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2012.74: State transitions in a model of intermittent seizure dynamics

2012.74: M Goodfellow, C Rummel, D Garry, G Baier, K Schindler and P Glendinning (2012) State transitions in a model of intermittent seizure dynamics.

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Abstract

We present a neural mass model of intermittent transitions into electroencephalographic (EEG) seizure rhythms in epilepsy. The route to intermittent dynamics is identied as Type 1 and state transition statistics are explored. It is demonstrated that a single framework can give rise to different distributions for seizure and non-seizure lengths in line with variability observed clinically. Further investigation of this model can give insight into the possible mechanisms underlying spontaneous seizure transitions in the epileptic brain.

Item Type:MIMS Preprint
Uncontrolled Keywords:CICADA
Subjects:PACS 2003 > 87 Biological and medical physics
MIMS number:2012.74
Deposited By:Professor Paul Glendinning
Deposited On:03 August 2012

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