State transitions in a model of intermittent seizure dynamics

Goodfellow, M and Rummel, C and Garry, D and Baier, G and Schindler, K and Glendinning, P (2012) State transitions in a model of intermittent seizure dynamics. [MIMS Preprint]

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We present a neural mass model of intermittent transitions into electroencephalographic (EEG) seizure rhythms in epilepsy. The route to intermittent dynamics is identied as Type 1 and state transition statistics are explored. It is demonstrated that a single framework can give rise to different distributions for seizure and non-seizure lengths in line with variability observed clinically. Further investigation of this model can give insight into the possible mechanisms underlying spontaneous seizure transitions in the epileptic brain.

Item Type: MIMS Preprint
Uncontrolled Keywords: CICADA
Subjects: PACS 2010, the AIP's Physics and Astronomy Classification Scheme > 80 INTERDISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY > 87 Biological and medical physics
Depositing User: Professor Paul Glendinning
Date Deposited: 03 Aug 2012
Last Modified: 08 Nov 2017 18:18

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