2012.74: State transitions in a model of intermittent seizure dynamics
2012.74: M Goodfellow, C Rummel, D Garry, G Baier, K Schindler and P Glendinning (2012) State transitions in a model of intermittent seizure dynamics.
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We present a neural mass model of intermittent transitions into electroencephalographic (EEG) seizure rhythms in epilepsy. The route to intermittent dynamics is identied as Type 1 and state transition statistics are explored. It is demonstrated that a single framework can give rise to different distributions for seizure and non-seizure lengths in line with variability observed clinically. Further investigation of this model can give insight into the possible mechanisms underlying spontaneous seizure transitions in the epileptic brain.
|Item Type:||MIMS Preprint|
|Subjects:||PACS 2003 > 87 Biological and medical physics|
|Deposited By:||Professor Paul Glendinning|
|Deposited On:||03 August 2012|