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2007.105: Review: Practical Design and Analysis of 2-Colour cDNA Microarray Experiments

2007.105: Ben Routley and Mark R. Muldoon (2007) Review: Practical Design and Analysis of 2-Colour cDNA Microarray Experiments.

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Abstract

This review paper, is aimed at biological researchers who are interested in or have begun to use cDNA microarrays for their investigations. Large microarray studies typically involve a multi-disciplinary team with various groups performing different aspects of the same experiment. This approach means that microarrays are less accessible to new researchers than more traditional biological techniques. This review aims to make current techniques of statistical design, normalisation and linear analysis of cDNA microarray experiments accessible to a wider community. These methods will be illustrated with examples that use freely-available packages implemented in Bioconductor and R.

Item Type:MIMS Preprint
Uncontrolled Keywords:cDNA microarray, data analysis
Subjects:MSC 2000 > 62 Statistics
MSC 2000 > 92 Biology and other natural sciences
MIMS number:2007.105
Deposited By:Dr Mark Muldoon
Deposited On:23 August 2007

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